Tadarise 60 mg contains Tadalafil 60 mg and is used for erectile dysfunction (ED). A 60 mg dose is higher than the commonly used ED doses of tadalafil, which are generally up to 20 mg when taken as needed. Higher doses can increase the chance of side effects and should only be used if specifically directed by a doctor. When Tadarise 60 mg may be risky: Heart disease, especially if ***** activity is not considered safe Low blood pressure or fainting problems Recent heart attack or stroke Severe liver or kidney problems (dose adjustment or avoidance may be needed) Do NOT take it with: Nitrate medicines for chest pain (such as nitroglycerin/isosorbide) — can cause a dangerous drop in blood pressure Riociguat Caution is needed with alpha-blockers, blood pressure medicines, and heavy alcohol use because blood pressure may fall too low. Possible side effects (more likely at higher doses): Headache Facial flushing Dizziness Indigestion Back pain or muscle aches Nasal congestion Vision or hearing changes in rare cases Seek urgent medical help if: You get chest pain, fainting, or severe dizziness You have sudden vision/hearing loss An erection lasts more than 4 hours If you tell me your age, whether you have BP/heart/diabetes problems, and whether you have taken tadalafil 10 mg or 20 mg before, I can help you judge the safety concerns more specifically.