Malegra (which contains sildenafil citrate) can cause side effects, and the timing of when you might feel them depends on how quickly the medication is absorbed and your individual sensitivity. Here’s a detailed breakdown: Onset of Side Effects Absorption: Malegra usually starts working within 30–60 minutes after taking a tablet. Peak effect: Side effects often appear around the same time the drug reaches peak blood levels — typically 1–2 hours after ingestion. Common Side Effects and Timing Side Effect Typical Onset Notes Headache 30–120 minutes Usually mild, resolves on its own Flushing (redness of face/neck) 30–60 minutes Common, may last 1–2 hours Dizziness 30–90 minutes Usually mild, avoid driving if severe Upset stomach/Nausea 30–60 minutes Take with food if persistent Nasal congestion 30–90 minutes Usually mild Back or muscle pain 2–4 hours Less common, usually mild Serious but Rare Side Effects Prolonged erection (>4 hours) → seek immediate medical attention Sudden vision or hearing changes → emergency Severe dizziness, fainting, or chest pain → emergency These serious side effects are rare, but they can occur anytime after taking Malegra, usually within the first few hours. Tips to Reduce Side Effects Take as prescribed — do not exceed the recommended dose. Avoid grapefruit juice, which can increase side effects. Limit alcohol — it may worsen headache, dizziness, or low blood pressure.