Filitra contains vardenafil, a PDE5 inhibitor like Vilitra, used for erectile dysfunction. Although rare, one of the serious but uncommon side effects linked to PDE5 inhibitors, including vardenafil (Filitra), is sudden hearing loss or hearing impairment. When can Filitra affect hearing? Timing: Hearing loss or ringing in the ears (tinnitus) can happen suddenly and usually occurs within hours to days after taking the medication. Nature: It’s often described as a sudden, unexplained decrease in hearing in one or both ears, sometimes accompanied by dizziness or ringing. Incidence: This side effect is very rare but is considered a medical emergency. What to do if hearing problems occur? Stop using Filitra immediately. Seek emergency medical attention or see a healthcare provider right away. Early treatment may improve the chance of recovery. Report any hearing changes to your doctor before continuing or starting any PDE5 inhibitor.