Malegra 120 mg can be used by men with hypertension, but it must be done carefully and under medical supervision. Since Malegra contains sildenafil citrate, which relaxes blood vessels, it can lower blood pressure slightly. For men whose hypertension is well controlled, this effect is usually mild and manageable. Important Precautions: Medication Interactions: Do not take Malegra 120 mg with nitrates or nitric oxide donors; this combination can cause a dangerous drop in blood pressure. Some antihypertensive drugs (like alpha-blockers) can interact; timing and dosage may need adjustment. Starting Dose: 120 mg is a high dose, so doctors may recommend starting with 50–100 mg first, especially in men with hypertension, to assess tolerance. Health Screening: Men with heart disease, history of stroke, kidney, or liver issues need careful evaluation before taking sildenafil.